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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク K-Ras(G12C) inhibitor 6 ： ウィキペディア英語版 K-Ras(G12C) inhibitor 6 K-Ras(G12C) inhibitor 6 is an irreversible inhibitor of oncogenic K-Ras(G12C), subverting the native nucleotide preference to favour GDP over GTP. Its family of inhibitors allosterically control GTP affinity and effector interactions by fitting inside a "pocket", or binding site, of mutant K-Ras. Investigators and pathologists previously thought that K-Ras is undruggable. However, Dr. Kevan M. Shokat and his colleagues, in the Howard Hughes Medical Institute (HHMI) at the University of California, recently reported a novel discovery of "Achilles heel" on K-RAs, and believed that it has real translational implications for patients with K-RAs mutation. ==See also== * http://www.selleckchem.com/products/k-ras-g12c-inhibitor-6.html 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「K-Ras(G12C) inhibitor 6」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.